Principles of molecular oncology /

" ... provides a bold new look at the evolution of our knowledge of cancer ... will prove both informative and intellectually satisfying."--E. Donnall Thomas, MD " ... [an] excellent book ... -- Professor Sir David J. Weatherall, FRS, Regius Professor of Medicine, University of Oxford...

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Other Authors: Bronchud, Miguel H.
Format: Book Electronic
Published:Totowa, N.J. : Humana Press, ©2000.
Online Access:SpringerLink - Full text online 
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Table of Contents:
  • Foreword / E. Donnall Thomas
  • Foreword / David J. Weatherall
  • Foreword / Derek Crowther
  • Preface
  • Color Plates
  • Contributors
  • Part I. Molecular Markers
  • 1. Selecting the Right Targets for Cancer Therapy / Miguel H. Bronchud
  • 2. Clinical Importance of Prognostic Factors: Moving from Scientifically Interesting to Clinically Useful / Daniel F. Hayes
  • 3. Genetic Markers in Sporadic Tumors / Antonella Aiello and Elena Tamborini and Milo Frattini and Federica Perrone and Maria Oggionni and Silvana Pilotti and Marco A. Pierotti
  • 4. Genetic Markers in Breast Tumors with Hereditary Predisposition / Tatyana A. Grushko and Olufunmilayo I. Olopade
  • 5. Cellular and Tissue Markers in Solid Tumors / Barbro Linderholm and Thomas Lindahl and John Öhd and Jonas Bergh
  • 6. Molecular and Pathologic Characterization of Human Tumors / Chris Jones and Ming-Qing Du and Sunil R. Lakhani
  • 7. Circulating Tumor Markers / Alan Horwich and Gill Ross
  • 8. Proteomics-Based Approaches: New Opportunities in Cancer Research / Rachel A. Craven and Peter J. Selby and Rosamonde E. Banks
  • Part II. Diseased Regulatory Pathways
  • 9. Growth Factor Signaling Pathways in Cancer / Daniel Kalderon
  • 10. Estrogen Action and Breast Cancer / Jennifer E. Fox and Hong Liu and V. Craig Jordan
  • 11. Cyclin-Dependent Kinases and Their Regulators as Potential Targets for Anticancer Therapeutics / Miguel H. Bronchud and Leonardo Brizuela and Jeno Gyuris and Muzammil M. Mansuri
  • 12. Angiogenesis Switch Pathways / Jaume Piulats and Francesc Mitjans
  • 13. Invasion and Metastasis / Maria Rosa Bani and Raffaella Giavazzi
  • 14. Molecular Pathways of Drug Resistance / Linda E. Bröker and José A. Rodriguez and Giuseppe Giaccone
  • 15. Genomic Instability, DNA Repair Pathways, and Cancer / Gabriel Capellá and Miguel Angel Peinado
  • Part III. Future Directions
  • 16. Immunotherapy for Human Cancer: Evidence and Obstacles / Angelo A. Cardoso and W. Nicholas Haining and Marina Leite and Sara Maia
  • 17. Treatment with Monoclonal Antibodies / Gisela Schwab and Lorin Roskos and and C. Geoffrey Davis
  • 18. Emerging Molecular Therapies: Drugs Interfering with Signal Transduction Pathways / Richard Baird and Paul Workman
  • 19. Treatment of Carcinogenesis / M. Suzanne Stratton and Steven P. Stratton and Sara O. Dionne and Patricia Thompson and Ian N. Jongewaard and Iman Hakim and Tarrah Dilley and Linda Garland and James Ranger-Moore and David S. Alberts and Frederick M. Ahmann
  • 20. Suicide Gene Therapy / Ion Niculescu-Duvaz and Caroline J. Springer
  • Glossary
  • Index

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